Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | ABL1 | P00519 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655819 | 0.85 | ABL1 (0.55) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL11059744 | 0.85 | MEN1 (0.66) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL10838273 | 0.81 | ALOX5 (0.55) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL1033102 | 0.80 | MAPT (0.47) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL10838815 | 0.78 | MEN1 (0.50) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL11054645 | 0.78 | MEN1 (0.61) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL10418480 | 0.75 | KMT2A (0.54) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11110453 | 0.74 | MEN1 (0.52) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL11863473 | 0.74 | MEN1 (0.72) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL11057349 | 0.73 | MEN1 (0.54) | MEN1KMT2AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447442-A | ANTIINFLAMMATORY, ANTIARTHRITIC, ANTIHISTAMINE, ANTIALLERGENS, ANALGESICS, BACTERICIDES, AND FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0070376-A1 | Heterocyclic substituted-amino-pyrazolines | AMERICAN CYANAMID COMPANY (US) | 1983-01-26 | — | — | EP | disclosed |
| US-4348527-A | ANALGESICS, BACTERICIDES, FUNGICIDES | AMERICAN CYANAMID COMPANY (US) | 1982-09-07 | — | — | US | disclosed |