Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD1 | O95696 | 1/20 | 0.33 |
| ▸ | TAF1 | P21675 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11059398 | 1.00 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2ALDH1A3HSD17B1HSD17B2 | |
| SCHEMBL11058233 | 0.99 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2ALDH1A3HSD17B1HSD17B2 | |
| SCHEMBL11064662 | 0.87 | PDE3B (0.40) | ALDH1A1SMN1; SMN2HSD17B1HSD17B2MAPT | |
| SCHEMBL11059736 | 0.84 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2ALDH1A3HSD17B1HSD17B2 | |
| SCHEMBL11065581 | 0.84 | MEN1 (0.32) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11062183 | 0.84 | MEN1 (0.32) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11062182 | 0.84 | MEN1 (0.32) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11059053 | 0.84 | GAA (0.30) | GAA | |
| SCHEMBL11065574 | 0.84 | MEN1 (0.32) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL11059000 | 0.83 | IP6K1 (0.37) | ALDH1A1HSD17B1HSD17B2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451462-A | Method of treating inflammation and pain using heteramino benzofurans | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | claimed |
| US-4426380-A | ANTIINFLAMMATORY, ANALGESIC, SUNSCREEN | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | claimed |
| EP-0078241-A2 | Furanes | CIBA-GEIGY AG (CH) | 1983-05-04 | — | — | EP | claimed |
| US-4451462-A | Method of treating inflammation and pain using heteramino benzofurans | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4426380-A | ANTIINFLAMMATORY, ANALGESIC, SUNSCREEN | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0078241-A2 | Furanes | CIBA-GEIGY AG (CH) | 1983-05-04 | — | — | EP | disclosed |