SCHEMBL11064753

SCHEMBL11064753

CC(=O)OCCN(C(=O)CCCCOc1ccc2c(c1)C(C)CC(=O)N2)C1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 20/20 0.50
PDE3A Q14432 20/20 0.50
PDE2A O00408 5/20 0.44
P2RY12 Q9H244 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11064605 0.89 PDE3B (0.58) PDE3BPDE3APDE2AP2RY12
SCHEMBL11061924 0.88 PDE3B (0.56) PDE3BPDE3APDE2AP2RY12
SCHEMBL11062198 0.87 PDE3B (0.49) PDE3BPDE3APDE2AP2RY12
SCHEMBL11061783 0.85 PDE3B (0.69) PDE3BPDE3A
SCHEMBL11067899 0.82 PDE3B (0.68) PDE3BPDE3A
SCHEMBL11064459 0.82 PDE3B (0.73) PDE3BPDE3A
SCHEMBL11065401 0.80 PDE3B (0.48) PDE3BPDE3APDE2AP2RY12
SCHEMBL11063314 0.79 PDE3B (0.55) PDE3BPDE3APDE2AP2RY12
SCHEMBL11065345 0.77 PDE3B (0.60) PDE3BPDE3A
SCHEMBL11062550 0.77 PDE3B (0.40) PDE3BPDE3APDE2AP2RY12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4435404-A ANTICOAGULANTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-03-06 US disclosed