Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 19/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 19/20 | 0.48 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061924 | 0.91 | PDE3B (0.56) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL11071572 | 0.84 | PDE3B (0.65) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11064605 | 0.84 | PDE3B (0.58) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL11063314 | 0.82 | PDE3B (0.55) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL11067728 | 0.81 | PDE3B (0.61) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11064753 | 0.80 | PDE3B (0.50) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL11062198 | 0.79 | PDE3B (0.49) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL11061424 | 0.79 | PDE3B (0.52) | PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL11071205 | 0.78 | PDE3B (0.62) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11067917 | 0.77 | PDE3B (0.65) | PDE3BPDE3APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |