⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18804388 | 0.79 | — | — | |
| SCHEMBL18827262 | 0.76 | — | — | |
| SCHEMBL18647232 | 0.76 | — | — | |
| SCHEMBL7999819 | 0.74 | ALDH1A1 (0.43) | — | |
| SCHEMBL18651683 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL5054649 | 0.72 | ALDH1A1 (0.48) | — | |
| SCHEMBL18647660 | 0.70 | — | — | |
| SCHEMBL18804428 | 0.70 | — | — | |
| SCHEMBL18804390 | 0.70 | — | — | |
| SCHEMBL18804457 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | claimed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | claimed |
| US-11767376-B2 | Catalyst mixture | ARLANXEO NETHERLANDS B.V. (NL) | 2023-09-26 | — | — | US | disclosed |
| US-11578148-B2 | Metal complex comprising amidine and thiophene fused cyclopentadienyl ligands | ARLANXEO NETHERLANDS B.V. | 2023-02-14 | — | — | US | disclosed |
| US-11560394-B2 | Metal complex comprising amidine and indole fused cyclopentadienyl ligands | ARLANXEO NETHERLANDS B.V. | 2023-01-24 | — | — | US | disclosed |
| US-20220056162-A1 | CATALYST MIXTURE | ARLANXEO NETHERLANDS B.V. (NL) | 2022-02-24 | — | — | US | disclosed |
| US-11185853-B2 | Catalysts for polycarbonate production | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2021-11-30 | — | — | US | disclosed |
| EP-3732183-B1 | METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands Bv (NL) | 2021-10-20 | — | — | EP | disclosed |
| EP-3853265-A1 | CATALYST MIXTURE | Arlanxeo Netherlands B.V. (NL) | 2021-07-28 | — | — | EP | disclosed |
| US-20210087305-A1 | METAL COMPLEX COMPRISING AMIDINE AND THIOPHENE FUSED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2021-03-25 | — | — | US | disclosed |
| EP-3781582-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands B.V. (NL) | 2021-02-24 | — | — | EP | disclosed |
| US-20090274650-A1 | INHIBITORS OF ASPARTYL PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED | 2009-11-05 | — | — | US | disclosed |
| US-7521470-B2 | Factor Xa inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2009-04-21 | — | — | US | disclosed |
| EP-1599535-B1 | POLYCARBONATE COMPOSITIONS | EASTMAN CHEM CO (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |
| US-5373008-A | Phenylamidine and phenylguanidine derivatives and their use as anti-diabetic agents | THE BOOTS COMPANT PLC. (GB) | 1994-12-13 | — | — | US | disclosed |
| WO-1994018181-A1 | PROCESS FOR PREPARING N-SUBSTITUTED-OXAZOLIDINE-2,4-DIONES | MONSANTO COMPANY (US) | 1994-08-18 | — | — | WO | disclosed |
| US-5223498-A | Hypoglycemic agents | THE BOOTS COMPANY PLC (GB) | 1993-06-29 | — | — | US | disclosed |
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | disclosed |
| EP-0385038-A1 | Ortho-substituted phenyl amidine and phenyl guanidine derivatives and antidiabetic or hypoglycaemic agents containing them | The Boots Company PLC (GB) | 1990-09-05 | — | — | EP | disclosed |