Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | LDHB | P07195 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066022 | 0.87 | CHRM1 (0.49) | MAPTSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL10984624 | 0.87 | ALDH1A1 (0.44) | MAPTSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL22296418 | 0.76 | MAPT (0.58) | MAPTSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL10994119 | 0.74 | CHRM1 (0.51) | MAPTSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL23537562 | 0.70 | MAPT (0.58) | MAPTSMN1; SMN2GAAALDH1A1ALDH3A1 | |
| SCHEMBL2387658 | 0.70 | HIF1A (0.50) | MAPTALDH1A1MEN1KMT2AHTT | |
| SCHEMBL23732094 | 0.68 | SLC6A2 (0.53) | MAPTSMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL23537930 | 0.68 | SMN1; SMN2 (0.64) | MAPTSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL12864867 | 0.68 | MAPT (0.64) | MAPTSMN1; SMN2GAAALDH1A1MEN1 | |
| SCHEMBL1665694 | 0.66 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2GAAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451462-A | Method of treating inflammation and pain using heteramino benzofurans | CIBA-GEIGY CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4426380-A | ANTIINFLAMMATORY, ANALGESIC, SUNSCREEN | CIBA-GEIGY CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |