SCHEMBL11064976

SCHEMBL11064976

CC(=O)OCCNC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
HSD17B10 Q99714 2/20 0.46
LMNA P02545 1/20 0.46
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CHRM5 P08912 2/20 0.43
CHRM1 P11229 2/20 0.43
CHRM3 P20309 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
PGR P06401 1/20 0.43
CHRM2 P08172 1/20 0.43
CHRM4 P08173 1/20 0.43
HTR1A P08908 1/20 0.43
CHRNB2 P17787 1/20 0.43
TBXA2R P21731 1/20 0.43
CHRNB4 P30926 1/20 0.43
CHRNA3 P32297 1/20 0.43
CHRNA7 P36544 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13921582 0.83 ALDH1A1 (0.46) ALDH1A1HSD17B10LMNAMEN1KMT2A
SCHEMBL279485 0.83 MAPK1 (0.50) ALDH1A1HSD17B10LMNAMEN1KMT2A
SCHEMBL13966179 0.82 EGLN1 (0.35) ALDH1A1HSD17B10LMNAMEN1KMT2A
SCHEMBL11064973 0.81 ALDH1A1 (0.44) ALDH1A1HSD17B10LMNAMEN1KMT2A
SCHEMBL11053682 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNAMEN1KMT2A
SCHEMBL9081898 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNAMEN1KMT2A
SCHEMBL18611045 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNAMEN1KMT2A
SCHEMBL9292563 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNAMEN1KMT2A
SCHEMBL17124613 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNAMEN1KMT2A
SCHEMBL11053678 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4387058-A HERBICIDES, FUNGICIDES, OR BACTERICIDES THE DOW CHEMICAL COMPANY (US) 1983-06-07 US claimed
US-4375546-A FUNGICIDES, HERBICIDES THE DOW CHEMICAL COMPANY (US) 1983-03-01 US claimed
US-4467101-A CEPHALOSPORIN PRECURSORS CIBA-GEIGY CORPORATION (US) 1984-08-21 US disclosed
US-4464366-A Cephem compounds having a terminal aminocarboxylic acid grouping and containing an azacyclyl(thio)ureido group CIBA GEIGY CORPORATION (US) 1984-08-07 US disclosed
EP-0016900-B1 INTERMEDIATES IN THE PREPARATION OF CEPHALOSPORIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND USE CIBA-GEIGY AG (CH) 1983-11-16 EP disclosed
US-4387058-A HERBICIDES, FUNGICIDES, OR BACTERICIDES THE DOW CHEMICAL COMPANY (US) 1983-06-07 US disclosed
EP-0076452-A2 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1983-04-13 EP disclosed
US-4375546-A FUNGICIDES, HERBICIDES THE DOW CHEMICAL COMPANY (US) 1983-03-01 US disclosed
US-4374134-A Cephalosporin compounds with terminal aminocarboxylic acid groupings and anti-bacterial use thereof CIBA-GEIGY CORPORATION (US) 1983-02-15 US disclosed
EP-0070803-A2 Antibiotically active aminotriazolylcephalosporin derivatives and their preparation CIBA-GEIGY AG (CH) 1983-01-26 EP disclosed
EP-0059683-A2 7-Acylamido-3-cephem-4-carboxylic acids, process for their preparation, pharmaceutical compositions containing them and their use CIBA-GEIGY AG (CH) 1982-09-08 EP disclosed
EP-0000500-B1 CEPHALOSPRIN DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM CIBA-GEIGY AG (CH) 1982-04-28 EP disclosed
US-4313945-A 7-Thiazolyl-acetamido-cephem derivatives with terminal aminocarboxylic acid grouping CIBA-GEIGY CORPORATION (US) 1982-02-02 US disclosed
EP-0037797-A2 Cephalosporin derivatives, process for their preparation, pharmaceutical compositions containing them and their application CIBA-GEIGY AG (CH) 1981-10-14 EP disclosed
EP-0031794-A2 Cephalosporin derivatives, process for their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1981-07-08 EP disclosed
EP-0022245-A2 Aminothiadiazolyl derivatives, process for their preparation, pharmaceutical compositions containing them;starting compounds and process for their preparation CIBA-GEIGY AG (CH) 1981-01-14 EP disclosed
EP-0016900-A1 Intermediates in the preparation of cephalosporin derivatives, process for their preparation and use CIBA-GEIGY AG (CH) 1980-10-15 EP disclosed
EP-0016296-A1 Cephalosporin derivatives, process for their preparation, compositions containing them, and intermediates and their preparation CIBA-GEIGY AG (CH) 1980-10-01 EP disclosed
EP-0000500-A2 Cephalosprin derivatives, process for their preparation and pharmaceutical compositions containing them CIBA-GEIGY AG (CH) 1979-02-07 EP disclosed