SCHEMBL11065009

SCHEMBL11065009

CCCCCCN1C(=O)CCc2cc(OCCCC(=O)N(CCO)C3CCCCC3)ccc21

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 20/20 0.52
PDE3A Q14432 20/20 0.52
PDE2A O00408 1/20 0.41
P2RY12 Q9H244 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11058450 0.89 PDE3B (0.49) PDE3BPDE3A
SCHEMBL11062167 0.87 PDE3B (0.57) PDE3BPDE3A
SCHEMBL11058996 0.87 PDE3B (0.50) PDE3BPDE3APDE2AP2RY12
SCHEMBL11065267 0.85 PDE3B (0.53) PDE3BPDE3AP2RY12
SCHEMBL11065451 0.85 PDE3B (0.53) PDE3BPDE3A
SCHEMBL11065280 0.84 PDE3B (0.47) PDE3BPDE3APDE2AP2RY12
SCHEMBL11065742 0.82 PDE3B (0.55) PDE3BPDE3APDE2AP2RY12
SCHEMBL11071221 0.77 PDE3B (0.56) PDE3BPDE3APDE2AP2RY12
SCHEMBL11064310 0.77 PDE3B (0.46) PDE3BPDE3APDE2AP2RY12
SCHEMBL11062440 0.76 PDE3B (0.51) PDE3BPDE3APDE2AP2RY12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4435404-A ANTICOAGULANTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-03-06 US disclosed