SCHEMBL11065451

SCHEMBL11065451

O=C1CCc2cc(OCCCC(=O)N(CCO)C3CCCCC3)ccc2N1Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 8/20 0.53
PDE3A Q14432 8/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11058636 0.90 PDE3B (0.44) PDE3BPDE3A
SCHEMBL11058450 0.90 PDE3B (0.49) PDE3BPDE3A
SCHEMBL11068764 0.88 PDE3B (0.43) PDE3BPDE3A
SCHEMBL11065267 0.86 PDE3B (0.53) PDE3BPDE3A
SCHEMBL11062167 0.85 PDE3B (0.57) PDE3BPDE3A
SCHEMBL11065009 0.85 PDE3B (0.52) PDE3BPDE3A
SCHEMBL11062867 0.83 HTR6 (0.44) PDE3BPDE3A
SCHEMBL11058996 0.83 PDE3B (0.50) PDE3BPDE3A
SCHEMBL11065742 0.79 PDE3B (0.55) PDE3BPDE3A
SCHEMBL11064454 0.77 POLB (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4435404-A ANTICOAGULANTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1984-03-06 US disclosed