Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.68 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | HTR2B | P41595 | 2/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | IDO1 | P14902 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | MIF | P14174 | 2/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.49 |
| ▸ | ACP3 | P15309 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30876859 | 0.96 | TAAR1 (0.67) | TAAR1HTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL429769 | 0.96 | TAAR1 (0.67) | TAAR1HTR2AHTR2BHTR2CIDO1 | |
| Ethylamine SCHEMBL28258055 | 0.95 | TAAR1 (0.71) | TAAR1HTR2AHTR2BHTR2CIDO1 | |
| Hydrochloric Acid SCHEMBL7988615 | 0.94 | TAAR1 (0.65) | TAAR1HTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL27360531 | 0.86 | TAAR1 (0.56) | TAAR1HTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL18015796 | 0.86 | TAAR1 (0.54) | TAAR1HTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL256694 | 0.85 | TAAR1 (0.62) | TAAR1HTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL7929109 | 0.84 | TAAR1 (0.61) | TAAR1HTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL2094737 | 0.82 | TAAR1 (0.59) | TAAR1HTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL28261580 | 0.82 | TAAR1 (0.59) | TAAR1HTR2AHTR2BHTR2CIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435396-A | FROM 2-AMINO-5-ACETYLOXAZOLE | PFIZER INC. (US) | 1984-03-06 | — | — | US | disclosed |