Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.38 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10545073 | 1.00 | MEN1 (0.42) | MEN1KMT2ACCKBRNAAALMNA | |
| SCHEMBL10546201 | 0.99 | MEN1 (0.43) | MEN1KMT2ACCKBRNAAALMNA | |
| SCHEMBL11398202 | 0.92 | MAPT (0.44) | MEN1KMT2ACCKBRNAAALMNA | |
| SCHEMBL10695608 | 0.89 | MEN1 (0.46) | MEN1KMT2ACCKBRNAAALMNA | |
| SCHEMBL10545151 | 0.87 | MEN1 (0.43) | MEN1KMT2ACCKBRNAAALMNA | |
| SCHEMBL10546563 | 0.86 | NAAA (0.39) | MEN1KMT2ACCKBRNAAAMAPT | |
| SCHEMBL10541610 | 0.85 | NAAA (0.37) | MEN1KMT2ACCKBRNAAAMAPT | |
| SCHEMBL11607687 | 0.83 | NAAA (0.40) | MEN1KMT2ANAAAASAH1 | |
| SCHEMBL11603305 | 0.83 | NAAA (0.40) | MEN1KMT2ANAAAASAH1 | |
| SCHEMBL11604798 | 0.82 | CNR2 (0.39) | MEN1KMT2ANAAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4550105-A | BETA-LACTAMASE INHIBITORS, ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1985-10-29 | — | — | US | disclosed |
| EP-0021678-A1 | 1-Sulpho-2-oxoazetidine derivatives, their production and pharmaceutical compositions thereof | Takeda Chemical Industries, Ltd. (JP) | 1981-01-07 | — | — | EP | disclosed |