Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | NOS3 | P29474 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | NOS2 | P35228 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785354 | 0.74 | IDO1 (0.53) | GAAIDO1NOS3NOS1NOS2 | |
| SCHEMBL5185939 | 0.74 | GAA (0.50) | GAAIDO1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11064823 | 0.72 | IDO1 (0.55) | GAAIDO1NOS3NOS1NOS2 | |
| SCHEMBL11530105 | 0.71 | GAA (0.48) | GAACYP1A2CYP2C9CYP2C19MAPT | |
| Bromide SCHEMBL4921073 | 0.71 | IDO1 (0.62) | GAAIDO1NOS3NOS1NOS2 | |
| SCHEMBL7400924 | 0.71 | HPGD (0.54) | GAACYP1A2MAPTL3MBTL1HPGD | |
| SCHEMBL7125566 | 0.70 | IDO1 (0.52) | GAAIDO1NOS3NOS1NOS2 | |
| Benzylamidinoisothiourea SCHEMBL13460125 | 0.69 | IDO1 (0.62) | GAAIDO1NOS3NOS1NOS2 | |
| SCHEMBL13256326 | 0.69 | IDO1 (0.52) | GAAIDO1NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL7397125 | 0.69 | HPGD (0.53) | GAACYP1A2MAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4475942-A | N-Phosphonomethylglycine derivatives and herbicidal compositions containing them | GESHURI LABORATORIES LTD. (IL) | 1984-10-09 | — | — | US | disclosed |
| EP-0103055-A1 | N-phosphonomethylglycine derivatives and herbicidal compositions containing them | Geshuri Laboratories Ltd. (IL) | 1984-03-21 | — | — | EP | disclosed |