Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | DRD2 | P14416 | 1/20 | 0.69 |
| ▸ | DRD4 | P21917 | 1/20 | 0.69 |
| ▸ | DRD3 | P35462 | 1/20 | 0.69 |
| ▸ | DCUN1D1 | Q96GG9 | 8/20 | 0.66 |
| ▸ | CCR3 | P51677 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | F10 | P00742 | 1/20 | 0.58 |
| ▸ | HPN | P05981 | 1/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.58 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.58 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.58 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.58 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | UBE2M | P61081 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337873 | 0.85 | DRD4 (0.71) | KMT2ADRD4DCUN1D1CCR3POLB | |
| SCHEMBL9078087 | 0.83 | DRD4 (1.00) | KMT2ADRD2DRD4DRD3DCUN1D1 | |
| SCHEMBL18658001 | 0.81 | DCUN1D1 (0.76) | KMT2ADRD2DRD4DRD3DCUN1D1 | |
| SCHEMBL18640380 | 0.81 | DCUN1D1 (0.74) | KMT2ADRD2DRD4DRD3DCUN1D1 | |
| SCHEMBL18658004 | 0.79 | DCUN1D1 (1.00) | KMT2ADRD2DRD4DRD3DCUN1D1 | |
| SCHEMBL18657999 | 0.79 | DRD4 (0.81) | KMT2ADRD2DRD4DRD3DCUN1D1 | |
| SCHEMBL18657822 | 0.77 | DCUN1D1 (0.81) | KMT2ADRD2DRD4DRD3DCUN1D1 | |
| SCHEMBL12677059 | 0.76 | DRD4 (0.85) | KMT2ADRD2DRD4DRD3DCUN1D1 | |
| SCHEMBL18657866 | 0.76 | DRD4 (0.85) | KMT2ADRD2DRD4DRD3DCUN1D1 | |
| SCHEMBL18658206 | 0.76 | F10 (0.79) | KMT2ADRD2DRD4DRD3DCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426387-A | Piperid-4-yl ureas and thio ureas used as anti-depressant agents | JOHN WYETH & BROTHER LTD. (GB) | 1984-01-17 | — | — | US | claimed |