Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29429340 | 0.88 | PARP1 (0.57) | PARP1HDAC8HDAC6SMN1; SMN2CYP2C19 | |
| SCHEMBL10945146 | 0.88 | CNR2 (0.50) | PARP1HDAC8HDAC6SMN1; SMN2CYP2C19 | |
| SCHEMBL12013627 | 0.87 | ACHE (0.50) | PARP1HDAC8HDAC6KMT2ATDP1 | |
| SCHEMBL855152 | 0.86 | PARP1 (0.59) | PARP1HDAC8HDAC6SMN1; SMN2CYP2C19 | |
| SCHEMBL16449231 | 0.82 | PARP1 (0.55) | PARP1HDAC8HDAC6SMN1; SMN2CYP2C19 | |
| SCHEMBL4434400 | 0.82 | PARP1 (0.55) | PARP1HDAC8HDAC6SMN1; SMN2CYP2C19 | |
| SCHEMBL12164013 | 0.82 | PARP1 (0.60) | PARP1HDAC8HDAC6SMN1; SMN2CYP2C19 | |
| SCHEMBL312610 | 0.80 | ACHE (0.62) | PARP1HDAC8HDAC6SMN1; SMN2KCNK3 | |
| SCHEMBL16331984 | 0.80 | CA12 (0.50) | HPGDMEN1KMT2ATDP1POLB | |
| SCHEMBL776798 | 0.79 | HDAC8 (0.53) | PARP1HDAC8HDAC6SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4442115-A | ANTI-ASTHMA | MAY & BAKER LIMITED (GB) | 1984-04-10 | — | — | US | disclosed |
| US-4321118-A | Bis benzoyl sensitizers for photopolymerization or photo cross linking process and composition | CIBA-GEIGY CORPORATION (US) | 1982-03-23 | — | — | US | disclosed |
| US-4318791-A | PHOTOPOLYMERIZABLE SYSTEM FOR INKS | CIBA-GEIGY CORPORATION (US) | 1982-03-09 | — | — | US | disclosed |
| US-4315807-A | Sensitizers for photopolymerization | CIBA-GEIGY CORPORATION (US) | 1982-02-16 | — | — | US | disclosed |
| US-4308400-A | AROMATIC HYDROXY KETONES | CIBA-GEIGY A.G. (CH) | 1981-12-29 | — | — | US | disclosed |