Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.52 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3972997 | 0.90 | KDM4E (0.63) | KDM4EPOLBALDH1A1HPGDGAA | |
| SCHEMBL6781993 | 0.88 | KDM4E (0.56) | KDM4EPOLBALDH1A1HPGDGAA | |
| SCHEMBL31335674 | 0.88 | GAA (0.54) | KDM4EPOLBALDH1A1HPGDGAA | |
| SCHEMBL2430255 | 0.87 | KDM4E (0.50) | KDM4EPOLBALDH1A1HPGDGAA | |
| SCHEMBL13468054 | 0.85 | KDM4E (0.49) | KDM4EPOLBALDH1A1HPGDGAA | |
| SCHEMBL27437761 | 0.85 | HTT (0.52) | KDM4EPOLBHPGDGAAHSD17B10 | |
| SCHEMBL26066718 | 0.84 | KDM4E (0.46) | KDM4EPOLBALDH1A1HPGDGAA | |
| SCHEMBL23703855 | 0.83 | KDM4E (0.47) | KDM4EPOLBALDH1A1HPGDGAA | |
| SCHEMBL14044062 | 0.83 | GAA (0.58) | KDM4EPOLBALDH1A1HPGDGAA | |
| SCHEMBL14032887 | 0.83 | KDM4E (0.47) | KDM4EPOLBALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4444567-A | ALKOXY BENZALDEHYDES, ALKOXY BENZOATES | PHILLIPS PETROLEUM COMPANY (US) | 1984-04-24 | — | — | US | disclosed |