Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11065578 | 0.90 | KDM4E (0.52) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL7378524 | 0.87 | KDM4E (0.73) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL13468054 | 0.86 | KDM4E (0.49) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL20366921 | 0.86 | KDM4E (0.53) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL6781993 | 0.86 | KDM4E (0.56) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL25134261 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL14044062 | 0.85 | GAA (0.58) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL14032887 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL18920679 | 0.85 | KDM4E (0.47) | KDM4EALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL25155768 | 0.85 | KDM4E (0.51) | KDM4EALDH1A1HPGDPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3169662-B1 | SUBSTITUTED VINYL- AND ALKINYL-CYANOCYCLOALKANOLS AND VINYL- AND ALKINYL-CYANOHETEROCYCLOALKANOLS AS AGENTS TO COMBAT ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2018-07-11 | — | — | EP | disclosed |
| US-20160243121-A1 | Quinazoline Derivatives, Compositions, and Uses Related Thereto | UNIV EMORY (US) | 2016-08-25 | — | — | US | disclosed |
| EP-2510786-A1 | Substituted Prop-2-in-1-ol and Prop-2-en-1-ol derivatives | Bayer CropScience AG (DE) | 2012-10-17 | — | — | EP | disclosed |
| WO-2009051417-A2 | PHENANTHRENE LACTAM DERIVATIVES HAVING ANTICANCER ACTIVITY AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2009-04-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160243121-A1 | Quinazoline Derivatives, Compositions, and Uses Related Thereto | NOX3, NOX1, NOX5 | KDM4E 1832/4885ALDH1A1 659/4885HPGD 70/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.