Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 5/20 | 0.35 |
| ▸ | FDPS | P14324 | 9/20 | 0.34 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11636360 | 1.00 | TSHR (0.38) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL9156559 | 1.00 | TSHR (0.38) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL8926607 | 0.82 | GGPS1 (0.38) | GGPS1SMPD1FDPSCES2LPAR1 | |
| SCHEMBL11636364 | 0.82 | GGPS1 (0.38) | GGPS1SMPD1FDPSCES2LPAR1 | |
| SCHEMBL9156566 | 0.82 | GGPS1 (0.38) | GGPS1SMPD1FDPSCES2LPAR1 | |
| SCHEMBL1921064 | 0.79 | ALDH1A1 (0.30) | TSHR | |
| SCHEMBL5026816 | 0.78 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL1160626 | 0.78 | TSHR (0.40) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL6658765 | 0.77 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS | |
| SCHEMBL11699499 | 0.77 | TSHR (0.44) | TSHRTHRBGGPS1SMPD1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446061-A | FIREPROOFING, SMOKELESS, PHOSPHITE/PHOSPHONATE | MONSANTO COMPANY (US) | 1984-05-01 | — | — | US | disclosed |
| US-4313761-A | FIREPROOFING AND SMOKE SUPPRESSANTS | MONSANTO COMPANY (US) | 1982-02-02 | — | — | US | disclosed |
| US-4260542-A | FLAME RETARDANTS, SMOKE SUPPRESSANTS | MONSANTO COMPANY (US) | 1981-04-07 | — | — | US | disclosed |
| US-4206133-A | FLAME RETARDANTS AND SMOKE SUPPRESSANTS | MONSANTO COMPANY (US) | 1980-06-03 | — | — | US | disclosed |
| US-4133823-A | FIREPROOFING, SMOKELESS | MONSANTO COMPANY (US) | 1979-01-09 | — | — | US | disclosed |