Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | DNTT | P04053 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11061963 | 0.88 | ALDH1A1 (0.40) | ALDH1A1DNTTCYP1A2HIF1APOLB | |
| SCHEMBL11062963 | 0.85 | DNTT (0.37) | ALDH1A1DNTTCYP1A2HIF1APOLB | |
| SCHEMBL11061158 | 0.82 | CYP1A2 (0.37) | ALDH1A1DNTTCYP1A2HIF1APOLB | |
| SCHEMBL11065468 | 0.78 | DNTT (0.36) | ALDH1A1DNTTCYP1A2HIF1APOLB | |
| SCHEMBL1577521 | 0.77 | ALDH1A1 (0.51) | ALDH1A1CYP1A2HIF1APOLBNPSR1 | |
| SCHEMBL10975655 | 0.77 | ALDH1A1 (0.47) | ALDH1A1DNTTCYP1A2HIF1APOLB | |
| SCHEMBL11064994 | 0.73 | ALDH1A1 (0.44) | ALDH1A1DNTTCYP1A2HIF1APOLB | |
| SCHEMBL11059939 | 0.72 | CYP1A2 (0.41) | ALDH1A1CYP1A2HIF1ATSHRKMT2A | |
| SCHEMBL15944453 | 0.72 | ALDH1A1 (0.61) | ALDH1A1DNTTCYP1A2HIF1APOLB | |
| SCHEMBL11062857 | 0.71 | DNTT (0.38) | ALDH1A1DNTTCYP1A2HIF1APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432378-A | ORGANOLEPTIC; TOBACCO; FOODS; DETERGENTS; COSMETICS | FRITZSCHE, DODGE & OLCOTT, INC. (US) | 1984-02-21 | — | — | US | disclosed |
| US-4326996-A | FOR PERFUMES | FRITZSCHE DODGE & OLCOTT INC. (US) | 1982-04-27 | — | — | US | disclosed |
| US-4281204-A | ALKYLATION, DECARBOXYLATION TO CYCLIZE | FRITZSCHE DODGE & OLCOTT INC. (US) | 1981-07-28 | — | — | US | disclosed |