⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8841964 | 0.73 | — | — | |
| SCHEMBL1434293 | 0.66 | — | — | |
| SCHEMBL8842268 | 0.61 | — | — | |
| SCHEMBL2554291 | 0.60 | — | — | |
| SCHEMBL1956229 | 0.58 | — | — | |
| SCHEMBL11025 | 0.58 | — | — | |
| SCHEMBL17319692 | 0.58 | — | — | |
| SCHEMBL1331159 | 0.56 | — | — | |
| SCHEMBL2538796 | 0.56 | — | — | |
| SCHEMBL10152903 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118076581-A | Iron death modulators, their preparation and use | 维泰瑞隆有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115916755-A | Azetidine cyclic ureas | 维泰瑞隆有限公司 | 2023-04-04 | — | — | CN | disclosed |
| CN-115697991-A | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-115697972-A | Receptor-interacting protein 1 inhibitors comprising piperazine heterocyclic amide ureas | 维泰瑞隆有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-109952300-B | 5-or 8-substituted imidazo [1,5-a ] pyridines | 百济神州有限公司 | 2022-01-18 | — | — | CN | disclosed |
| CN-107531693-B | 5 or 8-substituted imidazo [1, 5-a ] pyridines as indoleamine, tryptophan dioxygenase inhibitors | 百济神州有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-112165940-A | OX2R compound | 德克萨斯州立大学董事会 | 2021-01-01 | — | — | CN | disclosed |
| CN-111801334-A | Treatment of indolent or aggressive B-cell lymphomas using combinations comprising BTK inhibitors | 百济神州瑞士有限责任公司 | 2020-10-20 | — | — | CN | disclosed |
| EP-2174939-A1 | Pyranones useful as ATM inhibitors | Kudos Pharmaceuticals Limited (GB) | 2010-04-14 | — | — | EP | disclosed |
| US-4431808-A | ANTIDEPRESSANTS; TRANQUILIZERS; NEUROLEPTIC AGENTS | SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) | 1984-02-14 | — | — | US | disclosed |
| EP-0041410-B1 | TRICYCLIC ETHERS, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1983-11-09 | — | — | EP | disclosed |
| EP-0041410-A1 | Tricyclic ethers, processes for their preparation and their use as medicaments | SCIENCE UNION ET Cie SOCIETE FRANCAISE DE RECHERCHE MEDICALE (FR) | 1981-12-09 | — | — | EP | disclosed |
| US-4259208-A | STEREOSPECIFICITY ADDITIVE CONTAINING SULFIDE AND ETHER LINKAGES | ATO CHEMIE (FR) | 1981-03-31 | — | — | US | disclosed |