Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232522 | 0.86 | MAPT (0.38) | MAPTMEN1KMT2AALDH1A1AR | |
| SCHEMBL11134558 | 0.75 | MEN1 (0.40) | MAPTMEN1KMT2AALDH1A1AR | |
| SCHEMBL224946 | 0.75 | — | — | |
| SCHEMBL338711 | 0.75 | TRIM24 (0.41) | ALDH1A1KDM4EPTGS2HTT | |
| SCHEMBL29712437 | 0.75 | ALDH1A1 (0.60) | MAPTMEN1KMT2AALDH1A1AR | |
| SCHEMBL416655 | 0.75 | ALDH1A1 (0.60) | MAPTMEN1KMT2AALDH1A1AR | |
| SCHEMBL678299 | 0.72 | ALDH1A1 (1.00) | MAPTMEN1KMT2AALDH1A1AR | |
| SCHEMBL23975313 | 0.72 | ALDH1A1 (0.56) | MAPTMEN1KMT2AALDH1A1AR | |
| SCHEMBL6156438 | 0.71 | ALDH1A1 (0.61) | MAPTMEN1KMT2AALDH1A1AR | |
| SCHEMBL191668 | 0.70 | ATM (0.50) | MAPTMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457940-A | Carboxylic acid ester derivatives, process for manufacturing said derivatives, insecticides and acaricides containing said derivatives, and method for killing insects and acarina by treating therewith | DAINIPPON JOCHUGIKU KABUSHIKI KAISHA (JP) | 1984-07-03 | — | — | US | disclosed |