SCHEMBL11066174

SCHEMBL11066174

C=CO.O=C(O)NC(=O)O

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
ALDH1A1 P00352 3/20 0.32
TSHR P16473 2/20 0.32
FGFR4 P22455 1/20 0.32
KDM5B Q9UGL1 1/20 0.32
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29978 0.80
Bicarbonate SCHEMBL5974518 0.76
SCHEMBL29280194 0.76
Bicarbonate SCHEMBL28502389 0.76 LMNA (0.54) LMNAALDH1A1TSHRFGFR4ALOX15
SCHEMBL17273189 0.76
SCHEMBL11697459 0.76
SCHEMBL8101409 0.76 KDM5B (0.40) KDM5B
Ethyne SCHEMBL1652066 0.76
Hydrochloric Acid SCHEMBL20242223 0.76
SCHEMBL17273176 0.76 KDM5B (0.40) KDM5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4427410-A WASH CYCLE SOFTENING COLGATE-PALMOLIVE COMPANY (US) 1984-01-24 US disclosed
US-4409136-A Molecular sieve zeolite-built detergent paste COLGATE PALMOLIVE COMPANY (US) 1983-10-11 US disclosed