Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066557 | 0.99 | THRA (0.44) | KDM1ATHRATHRBPDE4APDE4B | |
| SCHEMBL11062982 | 0.99 | THRA (0.44) | KDM1ATHRATHRBPDE4APDE4B | |
| SCHEMBL11062485 | 0.99 | THRA (0.44) | KDM1ATHRATHRBPDE4APDE4B | |
| SCHEMBL11062469 | 0.99 | THRA (0.44) | KDM1ATHRATHRBPDE4APDE4B | |
| SCHEMBL11063194 | 0.99 | THRA (0.44) | KDM1ATHRATHRBPDE4APDE4B | |
| SCHEMBL12733729 | 0.93 | KDM1A (0.39) | KDM1ATHRATHRBPDE4APDE4B | |
| SCHEMBL10979460 | 0.92 | KDM1A (0.46) | KDM1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11063159 | 0.92 | KDM1A (0.46) | KDM1APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12733733 | 0.92 | THRA (0.39) | KDM1ATHRATHRBPDE4APDE4B | |
| SCHEMBL12733724 | 0.89 | KDM1A (0.40) | KDM1ATHRATHRBPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490305-A | Liquid-crystalline halogen compounds, process for their preparation, dielectrics containing these, and electro-optical display element | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-12-25 | — | — | US | disclosed |