Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 16/20 | 0.55 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11062463 | 0.99 | TBXAS1 (0.56) | TBXAS1SLC22A12NAPRT | |
| SCHEMBL11066572 | 0.84 | TBXAS1 (0.46) | TBXAS1 | |
| SCHEMBL11068494 | 0.79 | TBXAS1 (0.58) | TBXAS1NAPRT | |
| Hydrochloric Acid SCHEMBL11066261 | 0.78 | TBXAS1 (0.59) | TBXAS1NAPRT | |
| SCHEMBL11070290 | 0.76 | TBXAS1 (0.62) | TBXAS1NAPRT | |
| SCHEMBL11063546 | 0.76 | PPARA (0.56) | TBXAS1 | |
| SCHEMBL11060943 | 0.76 | TBXAS1 (0.65) | TBXAS1NAPRT | |
| Hydrochloric Acid SCHEMBL11065642 | 0.75 | TBXAS1 (0.63) | TBXAS1NAPRT | |
| SCHEMBL11062589 | 0.75 | SMN1; SMN2 (0.56) | TBXAS1SLC22A12 | |
| Hydrochloric Acid SCHEMBL11063651 | 0.75 | TBXAS1 (0.56) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4317828-A | ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | claimed |
| US-4427682-A | ANTICOAGULANTS, ANTIINFLAMMATORY, HYPOTENSIVE, OR ANTIALLERGEN AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1984-01-24 | — | — | US | disclosed |
| US-4317828-A | ANTIINFLAMMATORY AGENTS, HYPOTENSIVE AGENTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | disclosed |
| US-4271170-A | THROMBOXANE SYNTHETASE ENZYME INHIBITOR USEFUL IN TREATING INFLAMMATION, HYPERTENSION, THROMBUS, CEREBRAL APOPLEXY, ASTHMA, AND CARDIOVASCULAR DISORDERS | ONO PHARMACEUTICAL CO., LTD., (JP) | 1981-06-02 | — | — | US | disclosed |