SCHEMBL11066730

SCHEMBL11066730

CC(OCc1ccccc1)c1c[nH]nn1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RCE1 Q9Y256 1/20 0.37
TSHR P16473 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HTT P42858 2/20 0.36
SLC6A2 P23975 1/20 0.36
SLC6A4 P31645 1/20 0.36
SLC6A3 Q01959 1/20 0.36
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
MAPK1 P28482 1/20 0.36
MAPT P10636 1/20 0.35
SLC1A3 P43003 2/20 0.34
SLC1A2 P43004 2/20 0.34
SLC1A1 P43005 2/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10632921 0.79 CYP1A2 (0.36) RCE1TSHRSLC6A2SLC6A4SLC6A3
SCHEMBL2652668 0.71 CYP1A2 (0.39) SLC6A2SLC6A4SLC6A3CYP1A2IDO1
SCHEMBL14289858 0.71 SLC6A2 (0.47) RCE1TSHRALDH1A1SLC6A2SLC6A4
SCHEMBL2701985 0.71 SLC6A2 (0.47) RCE1TSHRALDH1A1SLC6A2SLC6A4
SCHEMBL9834069 0.70
SCHEMBL15437001 0.70 HTR2C (0.42) LMNAMEN1CYP2D6KMT2AHSD17B10
SCHEMBL2652667 0.70 CYP1A2 (0.38) SLC6A2SLC6A4SLC6A3CYP1A2
SCHEMBL194644 0.70 CYP1A2 (0.53) ALDH1A1SLC6A2SLC6A4SLC6A3HPGD
SCHEMBL9915100 0.69 TSHR (0.48) RCE1TSHRALDH1A1SLC6A2SLC6A4
SCHEMBL3303138 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4472395-A PLANT SAFENING AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1984-09-18 US disclosed