Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652668 | 0.81 | CYP1A2 (0.39) | CYP1A2EPHX1SLC6A2TAAR1MAOA | |
| SCHEMBL1715656 | 0.80 | SRR (0.40) | CYP1A2EPHX1SLC6A2TAAR1MAOA | |
| SCHEMBL2652667 | 0.79 | CYP1A2 (0.38) | CYP1A2EPHX1SLC6A2TAAR1MAOA | |
| SCHEMBL19526 | 0.78 | CYP1A2 (0.37) | CYP1A2EPHX1SLC6A2TAAR1MAOA | |
| SCHEMBL20262079 | 0.76 | EPHX1 (0.55) | CYP1A2EPHX1ALDH1A1L3MBTL1MEN1 | |
| SCHEMBL10632921 | 0.76 | CYP1A2 (0.36) | CYP1A2EPHX1SLC6A2TAAR1MAOA | |
| SCHEMBL10793187 | 0.74 | CYP1A2 (0.35) | CYP1A2EPHX1SLC6A2TAAR1MAOA | |
| SCHEMBL1369775 | 0.74 | SIGMAR1 (0.37) | CYP1A2EPHX1SLC6A2TAAR1MAOA | |
| SCHEMBL16836843 | 0.74 | CYP1A2 (0.50) | CYP1A2EPHX1SLC6A2TAAR1MAOA | |
| SCHEMBL9525219 | 0.73 | DPP4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110100009-B | Method for chemical ligation of nucleic acids | 伊鲁米那股份有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-112915211-B | PD-L1 targeted peptide drug conjugate and synthetic method and application thereof | 成都中医药大学 | 2022-05-06 | — | — | CN | claimed |
| CN-112915211-A | PD-L1 targeted peptide drug conjugate and synthetic method and application thereof | 成都中医药大学 | 2021-06-08 | — | — | CN | claimed |
| CN-112717141-A | Acid-sensitive target polypeptide doxorubicin conjugate and synthesis method and application thereof | 成都中医药大学 | 2021-04-30 | — | — | CN | claimed |
| CN-110100009-A | The chemical connection process of nucleic acid | 伊鲁米那股份有限公司 | 2019-08-06 | — | — | CN | claimed |
| CN-107648200-A | A kind of preparation and application of the accurate switching mode neoplasm targeted therapy system of tumour cell | 郑州大学 | 2018-02-02 | — | — | CN | claimed |
| CN-118715221-A | Tricyclic compounds and uses thereof | 希格生科（深圳）有限公司 | 2024-09-27 | — | — | CN | disclosed |
| WO-2024087251-A1 | CYSTEINE-RESIDUE-SPECIFIC CHEMICAL PROBE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 南京科络思生物科技有限公司 | 2024-05-02 | — | — | WO | disclosed |
| CN-110100009-B | Method for chemical ligation of nucleic acids | 伊鲁米那股份有限公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-107690582-B | Apparatus and method for sample analysis | 雅培制药有限公司 | 2023-10-20 | — | — | CN | disclosed |
| CN-115594649-A | Cysteine residue specific chemical probe and preparation method and application thereof | 南京科络思生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-112717141-B | Acid-sensitive target polypeptide doxorubicin conjugate and synthesis method and application thereof | 成都中医药大学 | 2022-05-17 | — | — | CN | disclosed |
| CN-112915211-B | PD-L1 targeted peptide drug conjugate and synthetic method and application thereof | 成都中医药大学 | 2022-05-06 | — | — | CN | disclosed |
| WO-2010099273-A1 | METHODS AND COMPOSITIONS FOR PROTEIN LABELLING | GENENTECH, INC. (US) | 2010-09-02 | — | — | WO | disclosed |
| CN-101679318-A | Development of Molecular Imaging Probes for Carbonic Anhydrase-IX Using Linkage Chemistry | SIEMENS MEDICAL SOLUTIONS | 2010-03-24 | — | — | CN | disclosed |
| CN-101600683-A | Therapeutic compounds | FIBROTECH THERAPEUTICS PTY LTD (AU) | 2009-12-09 | — | — | CN | disclosed |
| EP-2046810-A2 | METHOD OF COVALENTLY LINKING A CARBOHYDRATE OR POLYALKYLENE OXIDE TO A PEPTIDE, PRECURSORS FOR USE IN THE METHOD AND RESULTANT PRODUCTS. | UCL Business PLC (GB) | 2009-04-15 | — | — | EP | disclosed |
| EP-1996938-A2 | IMMOBILIZED PROTEINS AND METHODS AND USES THEREOF | University of Utah Research Foundation (US) | 2008-12-03 | — | — | EP | disclosed |
| WO-2008001109-A2 | METHOD OF COVALENTLY LINKING A CARBOHYDRATE OR POLYALKYLENE OXIDE TO A PEPTIDE, PRECURSORS FOR USE IN THE METHOD AND RESULTANT PRODUCTS | UCL BUSINESS PLC (GB) | 2008-01-03 | — | — | WO | disclosed |
| WO-2007112007-A2 | IMMOBILIZED PROTEINS AND METHODS AND USES THEREOF | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2007-10-04 | — | — | WO | disclosed |