Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 17/20 | 0.57 |
| ▸ | MAOA | P21397 | 16/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11070160 | 0.98 | MAOB (0.57) | MAOBMAOADRD2 | |
| Iodide SCHEMBL11071122 | 0.90 | MAOB (0.53) | MAOBMAOADRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL11065317 | 0.90 | MAOB (0.51) | MAOBMAOADRD2 | |
| Iodide SCHEMBL11063822 | 0.87 | MAOB (0.48) | MAOBMAOADRD2 | |
| Iodide SCHEMBL11068297 | 0.86 | DRD2 (0.58) | MAOBMAOADRD2DRD4DRD3 | |
| Iodide SCHEMBL11068406 | 0.86 | MAOB (0.48) | MAOBMAOADRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL11076015 | 0.85 | MAOB (0.48) | MAOBMAOADRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL11063001 | 0.85 | MAOB (0.65) | MAOBMAOADRD2 | |
| Iodide SCHEMBL11360009 | 0.83 | DRD2 (0.68) | MAOBMAOADRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL11070913 | 0.83 | DRD2 (0.52) | MAOBMAOADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |