⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31464904 | 0.79 | NQO1 (0.34) | — | |
| SCHEMBL426079 | 0.78 | — | — | |
| SCHEMBL9944597 | 0.77 | GABRA1 (0.30) | — | |
| SCHEMBL14999211 | 0.72 | GABRA1 (0.32) | — | |
| SCHEMBL8986270 | 0.67 | — | — | |
| SCHEMBL9331058 | 0.65 | NQO1 (0.34) | — | |
| SCHEMBL6629957 | 0.65 | — | — | |
| SCHEMBL8833394 | 0.65 | — | — | |
| SCHEMBL17205088 | 0.65 | — | — | |
| SCHEMBL14304289 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025020304-A1 | CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, CATALYST AND USE OF CATALYST | 中国石油天然气股份有限公司 | 2025-01-30 | — | — | WO | claimed |
| US-11744816-B2 | Fixed dose combinations and formulations comprising ETC1002 and ezetimibe and methods of treating or reducing the risk of cardiovascular disease | ESPERION THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-20230210800-A1 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS INC (US) | 2023-07-06 | — | — | US | disclosed |
| US-20180133177-A1 | Treatment of NASH with Gemcabene | NEUROBO PHARMACEUTICALS, INC. | 2018-05-17 | — | — | US | disclosed |
| US-20180064671-A1 | Fixed Dose Combinations and Formulations Comprising ETC1002 and Ezetimibe and Methods of Treating or Reducing the Risk of Cardiovascular Disease | GLAS AMERICAS LLC | 2018-03-08 | — | — | US | disclosed |
| US-9855240-B2 | Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2018-01-02 | — | — | US | disclosed |
| US-9849104-B2 | Treatment of NASH with gemcabene | GEMPHIRE THERAPEUTICS INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20170349516-A1 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. | 2017-12-07 | — | — | US | disclosed |
| US-20170172955-A1 | Treatment of Mixed Dyslipidemia | NEUROBO PHARMACEUTICALS, INC. | 2017-06-22 | — | — | US | disclosed |
| US-20170172954-A1 | Treatment of NASH with Gemcabene | NEUROBO PHARMACEUTICALS, INC. | 2017-06-22 | — | — | US | disclosed |
| US-20110237511-A1 | EP4 Receptor Agonist, Compositions and Methods Thereof | MERCK FROSST CANADA (CA) | 2011-09-29 | — | — | US | disclosed |
| US-20110195978-A1 | COMPOUNDS FOR TREATMENT OF ALZHEIMER'S DISEASE | PURDUE RESEARCH FOUNDATION (US) | 2011-08-11 | — | — | US | disclosed |
| US-7994330-B2 | Oxidizing p-xylene to terephthalic acid using a catalyst having a dicarboximide skeleton; hydrothermally treating the product with hot water, decomposing and removing catalyst impurities | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2011-08-09 | — | — | US | disclosed |
| US-20110071314-A1 | PROCESS FOR PRODUCING AROMATIC POLYCARBOXYLIC ACID | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2011-03-24 | — | — | US | disclosed |
| US-20110003860-A1 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. | 2011-01-06 | — | — | US | disclosed |
| US-7524986-B2 | Methods for producing aromatic carboxylic acids | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
| US-20080171881-A1 | Method for Producing Organic Compound and Method for Decomposing Compound Having Dicarboximide Skeleton | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2008-07-17 | — | — | US | disclosed |
| EP-1870394-A1 | METHOD FOR PRODUCING ORGANIC COMPOUND AND METHOD FOR DECOMPOSING COMPOUND HAVING DICARBOXYIMIDE SKELETON | Daicel Chemical Industries, Ltd. (JP) | 2007-12-26 | — | — | EP | disclosed |
| US-20070191634-A1 | Methods for producing aromatic carboxylic acids | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1734029-A1 | PROCESS FOR PRODUCING AROMATIC CARBOXYLIC ACID | Daicel Chemical Industries, Ltd. (JP) | 2006-12-20 | — | — | EP | disclosed |