⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25472224 | 1.00 | — | — | |
| SCHEMBL1106722 | 0.74 | — | — | |
| SCHEMBL1106723 | 0.74 | — | — | |
| SCHEMBL12021992 | 0.71 | — | — | |
| SCHEMBL8398004 | 0.70 | — | — | |
| SCHEMBL13383282 | 0.69 | CA1 (0.37) | — | |
| SCHEMBL3412400 | 0.67 | — | — | |
| SCHEMBL78498 | 0.67 | — | — | |
| SCHEMBL25140654 | 0.67 | — | — | |
| SCHEMBL45956 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11744816-B2 | Fixed dose combinations and formulations comprising ETC1002 and ezetimibe and methods of treating or reducing the risk of cardiovascular disease | ESPERION THERAPEUTICS, INC. (US) | 2023-09-05 | — | — | US | disclosed |
| US-20230210800-A1 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS INC (US) | 2023-07-06 | — | — | US | disclosed |
| EP-2649160-B1 | PROCESSES UTILIZING SOLVENT EXTRACTION | EXXONMOBIL CHEMICAL PATENTS INC (US) | 2022-03-16 | — | — | EP | disclosed |
| US-20180133177-A1 | Treatment of NASH with Gemcabene | NEUROBO PHARMACEUTICALS, INC. | 2018-05-17 | — | — | US | disclosed |
| US-20180064671-A1 | Fixed Dose Combinations and Formulations Comprising ETC1002 and Ezetimibe and Methods of Treating or Reducing the Risk of Cardiovascular Disease | GLAS AMERICAS LLC | 2018-03-08 | — | — | US | disclosed |
| US-9855240-B2 | Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof | AMARIN PHARMACEUTICALS IRELAND LIMITED (IE) | 2018-01-02 | — | — | US | disclosed |
| US-20170349516-A1 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. | 2017-12-07 | — | — | US | disclosed |
| US-20170172955-A1 | Treatment of Mixed Dyslipidemia | NEUROBO PHARMACEUTICALS, INC. | 2017-06-22 | — | — | US | disclosed |
| CN-104011061-B | As HCV rna replicon inhibitor 2 ', ' the methyl substituted nucleoside derivates of 4 ' difluoro 2 | 里博科学有限责任公司 | 2017-06-13 | — | — | CN | disclosed |
| US-9662307-B2 | Compositions comprising eicosapentaenoic acid and a hydroxyl compound and methods of use thereof | THE REGENTS OF THE UNIVERSITY OF COLORADO (US) | 2017-05-30 | — | — | US | disclosed |
| US-20120225908-A1 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2012-09-06 | — | — | US | disclosed |
| US-20120172337-A1 | CYCLOALKYL-HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2012-07-05 | — | — | US | disclosed |
| US-20120135146-A1 | METHODS OF FORMING TOPOGRAPHICAL FEATURES USING SEGREGATING POLYMER MIXTURES | JSR CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |
| US-20120129930-A1 | KETONE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2012-05-24 | — | — | US | disclosed |
| US-8153690-B2 | Cycloalkyl-hydroxyl compounds and compositions for cholesterol management | ESPERION THERAPEUTICS, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| US-20110003860-A1 | HYDROXYL COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. | 2011-01-06 | — | — | US | disclosed |
| US-7449277-B2 | Positive resist compositions and patterning process | SHIN-ETSU CHEMICAL C., LTD (JP) | 2008-11-11 | — | — | US | disclosed |
| US-20080261147-A1 | Photoactive Compounds | RAHMAN M DALIL | 2008-10-23 | — | — | US | disclosed |
| US-7358408-B2 | Photoactive compounds | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2008-04-15 | — | — | US | disclosed |
| US-20080058542-A1 | Photoactive Compounds | RAHMAN M D | 2008-03-06 | — | — | US | disclosed |