Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.80 |
| ▸ | HPGD | P15428 | 4/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.80 |
| ▸ | DRD3 | P35462 | 1/20 | 0.77 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | RAD52 | P43351 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11406037 | 0.91 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL13923341 | 0.91 | DRD3 (0.79) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL32659736 | 0.91 | KDM4E (0.81) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL9344503 | 0.89 | KDM4E (0.79) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| Pefloxacin SCHEMBL34292 | 0.87 | DRD3 (1.00) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| Pefloxacin SCHEMBL28251251 | 0.87 | DRD3 (1.00) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL10027766 | 0.87 | DRD3 (0.84) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| Pefloxacin SCHEMBL29351730 | 0.87 | DRD3 (1.00) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| Pefloxacin SCHEMBL8184732 | 0.86 | DRD3 (0.98) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| Pefloxacin SCHEMBL10911017 | 0.86 | DRD3 (0.98) | KDM4EALDH1A1HPGDHSD17B10DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472579-A | REACTING A PIPERAZINE WITH A CHLORO QUINOLINECARBOXYLIC ACID ESTER, HYDROLYSIS | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1984-09-18 | — | — | US | disclosed |