Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.79 |
| ▸ | HPGD | P15428 | 4/20 | 0.79 |
| ▸ | BRD4 | O60885 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.78 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.78 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | RAD52 | P43351 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13923331 | 0.91 | KDM4E (0.79) | KDM4EALDH1A1HSD17B10HPGDBRD4 | |
| SCHEMBL9634547 | 0.91 | KDM4E (0.79) | KDM4EALDH1A1HSD17B10HPGDBRD4 | |
| SCHEMBL32659736 | 0.90 | KDM4E (0.81) | KDM4EALDH1A1HSD17B10HPGDBRD4 | |
| SCHEMBL11967716 | 0.90 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10HPGDBRD4 | |
| SCHEMBL9426943 | 0.90 | KDM4E (0.71) | KDM4EALDH1A1HSD17B10HPGDBRD4 | |
| SCHEMBL11067262 | 0.89 | KDM4E (0.80) | KDM4EALDH1A1HSD17B10HPGDLMNA | |
| Hydrochloric Acid SCHEMBL6776533 | 0.89 | KDM4E (0.70) | KDM4EALDH1A1HSD17B10HPGDBRD4 | |
| SCHEMBL10028896 | 0.88 | KDM4E (0.84) | KDM4EALDH1A1HSD17B10HPGDBRD4 | |
| Norfloxacin SCHEMBL3473 | 0.88 | ALDH1A1 (1.00) | KDM4EALDH1A1HSD17B10HPGDBRD4 | |
| Norfloxacin SCHEMBL2221304 | 0.88 | ALDH1A1 (1.00) | KDM4EALDH1A1HSD17B10HPGDBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163923-B2 | Bactericides, fungicides, viricides | CELMED ONCOLOGY (USA), INC. (CA) | 2007-01-16 | — | — | US | disclosed |
| EP-0351889-B1 | Process for the preparation of a quinoline carboxylic acid | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1994-06-29 | — | — | EP | disclosed |
| US-5294712-A | Process for the preparation of quinoline carboxylic acids | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1994-03-15 | — | — | US | disclosed |
| US-5284950-A | Process for the preparation of quinoline carboxyolic acids | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1994-02-08 | — | — | US | disclosed |
| EP-0249620-B1 | PROCESS FOR THE PREPARATION OF QUINOLINE CARBOXYLIC ACIDS | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1992-11-19 | — | — | EP | disclosed |
| US-4981966-A | Process for the preparation of quinoline carboxylic acids | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1991-01-01 | — | — | US | disclosed |
| EP-0351889-A1 | Process for the preparation of a quinoline carboxylic acid | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1990-01-24 | — | — | EP | disclosed |
| EP-0249620-A1 | PROCESS FOR THE PREPARATION OF QUINOLINE CARBOXYLIC ACIDS. | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1987-12-23 | — | — | EP | disclosed |
| WO-1987003587-A1 | PROCESS FOR THE PREPARATION OF QUINOLINE CARBOXYLIC ACIDS | Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. (HU) | 1987-06-18 | — | — | WO | disclosed |
| US-4472579-A | REACTING A PIPERAZINE WITH A CHLORO QUINOLINECARBOXYLIC ACID ESTER, HYDROLYSIS | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1984-09-18 | — | — | US | disclosed |
| US-4448962-A | BACTERICIDES | KYORIN SEIYAKU KABUSHIKI KAISHA | 1984-05-15 | — | — | US | disclosed |