Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 5/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071312 | 0.82 | CYP1A2 (0.40) | MEN1KMT2APDE10ATSHRCYP2C19 | |
| SCHEMBL11067252 | 0.78 | FABP3 (0.38) | MEN1KMT2ALMNACYP2C19CYP1A2 | |
| SCHEMBL11071338 | 0.72 | POLB (0.43) | MEN1KMT2ALMNAHTTKDM4E | |
| SCHEMBL11563216 | 0.71 | MEN1 (0.51) | MEN1KMT2ADHODHPDE10ATSHR | |
| SCHEMBL11071371 | 0.70 | NOTUM (0.39) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL11066940 | 0.70 | NOTUM (0.39) | MEN1KMT2ALMNAHTTKDM4E | |
| SCHEMBL11077329 | 0.70 | KDM4E (0.47) | CYP2C9KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL11075539 | 0.68 | USP2 (0.44) | MEN1KMT2ATSHRCYP2C19CYP1A2 | |
| SCHEMBL11072647 | 0.67 | TSHR (0.46) | LMNATSHRCYP2C19CYP2C9HTT | |
| SCHEMBL6409798 | 0.61 | CYP1A2 (0.66) | KMT2ANTRK1CYP2C19CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482555-A | ANTIINFLAMMATORY, ANTIARTHRITIC AGENTS, AND ANALGESIC | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-11-13 | — | — | US | disclosed |