Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | HPD | P32754 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071338 | 0.89 | POLB (0.43) | NOTUMKMT2ALMNAHTTNPC1 | |
| SCHEMBL11071312 | 0.88 | CYP1A2 (0.40) | NOTUMKMT2AHTTRAB9AL3MBTL1 | |
| SCHEMBL11071371 | 0.87 | NOTUM (0.39) | NOTUMKMT2ALMNANPC1RAB9A | |
| SCHEMBL11068662 | 0.79 | PKM (0.46) | NOTUMKMT2ALMNAHTTKDM4E | |
| SCHEMBL11072327 | 0.79 | ALOX12 (0.41) | KMT2ALMNAHTTPOLBMEN1 | |
| SCHEMBL23147251 | 0.75 | POLB (0.53) | NOTUMHTTSMN1; SMN2L3MBTL1POLB | |
| SCHEMBL11067981 | 0.74 | SLC11A2 (0.40) | KMT2ASMN1; SMN2KDM4EPOLB | |
| SCHEMBL11072182 | 0.73 | KDM4E (0.44) | NOTUMKMT2ALMNANPC1RAB9A | |
| SCHEMBL11067252 | 0.71 | FABP3 (0.38) | KMT2ALMNAKDM4EPOLBMEN1 | |
| SCHEMBL11075539 | 0.71 | USP2 (0.44) | KMT2AHTTL3MBTL1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482555-A | ANTIINFLAMMATORY, ANTIARTHRITIC AGENTS, AND ANALGESIC | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-11-13 | — | — | US | disclosed |