Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 19/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 19/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.40 |
| ▸ | PDE2A | O00408 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071217 | 0.84 | PDE3B (0.48) | PDE3BPDE3AP2RY12 | |
| SCHEMBL11067928 | 0.84 | PDE3B (0.48) | PDE3BPDE3AP2RY12 | |
| SCHEMBL11061924 | 0.82 | PDE3B (0.56) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL11068086 | 0.79 | PDE3B (0.42) | PDE3BPDE3A | |
| SCHEMBL11058328 | 0.79 | PDE3B (0.49) | PDE3BPDE3AP2RY12 | |
| SCHEMBL11064304 | 0.79 | PDE3B (0.46) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL11069955 | 0.79 | PDE3B (0.50) | PDE3BPDE3A | |
| SCHEMBL11062523 | 0.77 | PDE3B (0.49) | PDE3BPDE3APDE4APDE4BPDE4C | |
| SCHEMBL11063314 | 0.76 | PDE3B (0.55) | PDE3BPDE3AP2RY12PDE2A | |
| SCHEMBL11071596 | 0.76 | PDE3B (0.41) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |