Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 9/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 9/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067928 | 0.95 | PDE3B (0.48) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11071217 | 0.95 | PDE3B (0.48) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11071596 | 0.90 | PDE3B (0.41) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11058328 | 0.90 | PDE3B (0.49) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11062523 | 0.86 | PDE3B (0.49) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11061068 | 0.84 | ADRB2 (0.42) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11065568 | 0.83 | ADRB2 (0.42) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11066038 | 0.83 | PDE3B (0.47) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11068008 | 0.82 | PDE3B (0.45) | PDE3BPDE3AADRB2ADRB1HTR1A | |
| SCHEMBL11061846 | 0.82 | PDE3B (0.43) | PDE3BPDE3AADRB2ADRB1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |