Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.69 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4743903 | 1.00 | KDM4E (1.00) | KDM4EMAPTALDH1A1HSD17B10S1PR3 | |
| SCHEMBL4743901 | 1.00 | KDM4E (1.00) | KDM4EMAPTALDH1A1HSD17B10S1PR3 | |
| SCHEMBL16084531 | 0.92 | KDM4E (0.84) | KDM4EMAPTALDH1A1HSD17B10S1PR3 | |
| SCHEMBL11373045 | 0.85 | KDM4E (0.74) | KDM4EMAPTALDH1A1HSD17B10S1PR3 | |
| SCHEMBL2029800 | 0.85 | ALDH1A1 (0.76) | KDM4EMAPTALDH1A1HSD17B10S1PR3 | |
| SCHEMBL2034753 | 0.85 | ALDH1A1 (0.76) | KDM4EMAPTALDH1A1HSD17B10S1PR3 | |
| SCHEMBL31714043 | 0.85 | ALDH1A1 (0.76) | KDM4EMAPTALDH1A1HSD17B10S1PR3 | |
| SCHEMBL5526027 | 0.85 | ALDH1A1 (0.76) | KDM4EMAPTALDH1A1HSD17B10S1PR3 | |
| SCHEMBL3059385 | 0.85 | ALDH1A1 (0.76) | KDM4EMAPTALDH1A1HSD17B10S1PR3 | |
| SCHEMBL2034755 | 0.85 | ALDH1A1 (0.76) | KDM4EMAPTALDH1A1HSD17B10S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021255156-A1 | NOVEL DIPEPTIDE COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND A NOVEL THERAPEUTIC USE OF DIPEPTIDE COMPOUNDS | Universite Paris-Saclay (FR) | 2021-12-23 | — | — | WO | disclosed |
| US-4457935-A | ANGIOTENSIN-CONVERTING ENZYME INHIBITOR | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-07-03 | — | — | US | disclosed |
| US-4430344-A | Antihypertensive 4-thiazolidinecarboxylic acids | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-02-07 | — | — | US | disclosed |
| US-4423054-A | Antihypertensive 4-thiazolidinecarboxylic acids (substituted alkyl derivatives) | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1983-12-27 | — | — | US | disclosed |
| US-4386096-A | ANGIOTENSIN-CONVERTING ENZYME INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1983-05-31 | — | — | US | disclosed |
| US-4374249-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-02-15 | — | — | US | disclosed |
| US-4356183-A | ENZYME INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1982-10-26 | — | — | US | disclosed |