Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 3/20 | 0.52 |
| ▸ | ATP4B | P51164 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066607 | 0.89 | PPARG (0.45) | ATP4AATP4BHRH3MAPK1MEN1 | |
| SCHEMBL2191622 | 0.88 | ATP4A (0.55) | ATP4AATP4BHRH3MAPK1MEN1 | |
| SCHEMBL2193708 | 0.88 | ATP4A (0.54) | ATP4AATP4BHRH3MAPK1MEN1 | |
| SCHEMBL11064845 | 0.86 | PPARG (0.61) | ATP4AATP4BHRH3MAPK1MEN1 | |
| SCHEMBL14290284 | 0.85 | ATP4A (0.52) | ATP4AATP4BHRH3MAPK1MEN1 | |
| SCHEMBL10533298 | 0.84 | ATP4A (0.59) | ATP4AATP4BHRH3MAPK1MEN1 | |
| SCHEMBL11064082 | 0.83 | PPARG (0.64) | MAPK1MEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL102842 | 0.82 | ATP4A (0.46) | ATP4AATP4BHRH3MAPK1MEN1 | |
| SCHEMBL11098840 | 0.82 | DRD4 (0.44) | ALDH1A1PPARGL3MBTL1 | |
| SCHEMBL2189993 | 0.82 | ATP4A (0.60) | ATP4AATP4BHRH3MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033094-B1 | IMIDAZO(1,2-A)PYRIDINES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1984-10-10 | — | — | EP | disclosed |
| US-4450164-A | ANTIULCER AND ANTISECRETORY AGENTS | SCHERING CORPORATION (US) | 1984-05-22 | — | — | US | disclosed |
| EP-0033094-A1 | Imidazo(1,2-a)pyridines, processes for their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1981-08-05 | — | — | EP | disclosed |