Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.58 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.58 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.57 |
| ▸ | SCD | O00767 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SLC27A1 | Q6PCB7 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27722988 | 0.86 | GRM5 (0.61) | GRM5GRM1SLC6A7SCDHRH3 | |
| SCHEMBL3844701 | 0.85 | SLC6A7 (0.62) | GRM5GRM1SLC6A7SCDHRH3 | |
| SCHEMBL5987878 | 0.83 | GRM5 (0.58) | GRM5GRM1SLC6A7SCDHRH3 | |
| SCHEMBL29102030 | 0.82 | — | — | |
| SCHEMBL24937779 | 0.80 | GRM5 (0.54) | GRM5GRM1SLC6A7SCDHRH3 | |
| SCHEMBL11071509 | 0.80 | GRM5 (0.54) | GRM5GRM1SLC6A7SCDHRH3 | |
| SCHEMBL18701819 | 0.80 | GRM5 (0.54) | GRM5GRM1SLC6A7SCDHRH3 | |
| SCHEMBL5178383 | 0.80 | GRM5 (0.54) | GRM5GRM1SLC6A7SCDHRH3 | |
| SCHEMBL3146878 | 0.80 | GRM5 (0.54) | GRM5GRM1SLC6A7SCDHRH3 | |
| SCHEMBL4155820 | 0.80 | GRM5 (0.54) | GRM5GRM1SLC6A7SCDHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2712616-B1 | Intermediates for the preparation of 1-(acetyl)-piperidine and 1-(acetyl)-piperazine derivatives as fungicides for use in plant protection | DU PONT (US) | 2017-04-19 | — | — | EP | disclosed |
| US-4476128-A | ANTIARTHRITIC AGENTS ANTIBODY INHIBITORS | MITSUITOATSU CHEMICALS, INC. (JP) | 1984-10-09 | — | — | US | disclosed |