Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11066410 | 0.93 | KDM4E (0.60) | KDM4EALDH1A1GAAKMT2ALMNA | |
| SCHEMBL11029455 | 0.88 | KDM4E (0.47) | KDM4EALDH1A1PPARAGAAKMT2A | |
| SCHEMBL10338168 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1PPARAGAALMNA | |
| SCHEMBL8088792 | 0.82 | KDM4E (0.60) | KDM4EALDH1A1PPARAGAAKMT2A | |
| SCHEMBL9625908 | 0.82 | KDM4E (0.69) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL7918656 | 0.80 | LIG1 (0.48) | KDM4EALDH1A1GAAKMT2ALMNA | |
| SCHEMBL9627195 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL9625662 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL9625872 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1GAALMNAMAPT | |
| SCHEMBL9626411 | 0.80 | KDM4E (0.67) | KDM4EALDH1A1GAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468524-A | Alkenylphenyl substituted acrylates or methacrylates | CIBA-GEIGY CORPORATION (US) | 1984-08-28 | — | — | US | disclosed |
| US-4387204-A | Self-crosslinkable monomer composition containing alkenylphenyl substituted acrylates or methacrylates | CIBA-GEIGY CORPORATION (US) | 1983-06-07 | — | — | US | disclosed |
| EP-0038300-A1 | Polymerisable composition and (meth)acrylic ester | CIBA-GEIGY AG (CH) | 1981-10-21 | — | — | EP | disclosed |