Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068263 | 0.88 | KDM4E (0.59) | KDM4EALDH1A1PPARAKMT2AGAA | |
| SCHEMBL7898719 | 0.84 | JAK2 (0.40) | GAALMNA | |
| SCHEMBL11066410 | 0.81 | KDM4E (0.60) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL11029458 | 0.79 | KDM4E (0.47) | KDM4EGABRA1GABRB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL3458335 | 0.78 | GABRA1 (0.51) | KDM4EGABRA1GABRB2ALDH1A1ELANE | |
| SCHEMBL7856426 | 0.78 | PTGDR2 (0.56) | KDM4EGABRA1GABRB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL150620 | 0.77 | ALDH1A1 (0.46) | KDM4EALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14695733 | 0.76 | GABRA1 (0.53) | KDM4EGABRA1GABRB2ALDH1A1SMN1; SMN2 | |
| SCHEMBL15283971 | 0.76 | GAA (0.53) | KDM4ESMN1; SMN2GAALMNAHPGD | |
| SCHEMBL10454511 | 0.75 | GABRA1 (0.54) | KDM4EGABRA1GABRB2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60127317-A | — | — | None | — | — | JP | disclosed |
| JP-S60127317-A | MANUFACTURE OF CURABLE COMPOSITION | TOAGOSEI CHEM IND CO LTD | 1985-07-08 | — | — | JP | disclosed |