Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CCL2 | P13500 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10375397 | 0.75 | BRD4 (0.36) | BRD4CCL2HTR2AATM | |
| SCHEMBL8003375 | 0.70 | BRD4 (0.35) | BRD4CCL2HTR2AATM | |
| SCHEMBL11611849 | 0.66 | ATM (0.34) | BRD4CCL2ATM | |
| SCHEMBL17284105 | 0.64 | BRD4 (0.36) | BRD4CCL2HTR2AATM | |
| SCHEMBL11348748 | 0.63 | BRD4 (0.41) | BRD4CCL2HTR2AATM | |
| Hydrochloric Acid SCHEMBL11111763 | 0.63 | BRD4 (0.35) | BRD4CCL2HTR2AATM | |
| SCHEMBL11041396 | 0.62 | BRD4 (0.34) | BRD4CCL2HTR2AATM | |
| SCHEMBL418352 | 0.60 | BRD4 (0.38) | BRD4CCL2HTR2AATM | |
| SCHEMBL4958554 | 0.59 | BRD4 (0.37) | BRD4CCL2HTR2AATM | |
| SCHEMBL230905 | 0.58 | BRD4 (0.36) | BRD4CCL2HTR2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479948-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-10-30 | — | — | US | disclosed |
| US-4479948-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-10-30 | — | — | US | disclosed |
| US-4479948-A | HYPOTENSIVE AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-10-30 | — | — | US | disclosed |
| EP-0069953-A1 | Triazino-(2,1-a)-isoquinoline derivatives, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-01-19 | — | — | EP | disclosed |