Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | DPP4 | P27487 | 3/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2399008 | 1.00 | PHGDH (0.42) | PHGDHRECQLACEMAPTHSD11B1 | |
| SCHEMBL3054043 | 1.00 | PHGDH (0.42) | PHGDHRECQLACEMAPTHSD11B1 | |
| SCHEMBL16279354 | 0.90 | RECQL (0.54) | RECQLACEMAPTHSD11B1MGLL | |
| SCHEMBL19223831 | 0.90 | RECQL (0.54) | RECQLACEMAPTHSD11B1MGLL | |
| SCHEMBL2397617 | 0.90 | RECQL (0.54) | RECQLACEMAPTHSD11B1MGLL | |
| SCHEMBL21138526 | 0.90 | RECQL (0.54) | RECQLACEMAPTHSD11B1MGLL | |
| SCHEMBL11633781 | 0.77 | NSD2 (0.32) | — | |
| SCHEMBL31664963 | 0.77 | NSD2 (0.32) | — | |
| SCHEMBL31664983 | 0.77 | NSD2 (0.32) | — | |
| SCHEMBL11743297 | 0.77 | MEN1 (0.50) | RECQLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4427683-A | Antiinflammatory 2'-pyridyl-1'-oxide carbothiolate and carbodithioate compounds | SDS BIOTECH CORPORATION (US) | 1984-01-24 | — | — | US | disclosed |
| EP-0089661-A1 | Antiinflammatory 2'-pyridyl-1'-oxide carbothiolate and carbodithioate compounds | SDS BIOTECH CORPORATION (US) | 1983-09-28 | — | — | EP | disclosed |