SCHEMBL2397617

SCHEMBL2397617

CC1CCCC(C)N1C(=O)Cl

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.54
MGLL Q99685 1/20 0.46
ACE P12821 1/20 0.46
HSD11B1 P28845 1/20 0.44
ALDH1A1 P00352 4/20 0.43
HPGD P15428 2/20 0.43
GLA P06280 1/20 0.43
MAPT P10636 1/20 0.40
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MCOLN3 Q8TDD5 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ACHE P22303 1/20 0.39
KMT2A Q03164 2/20 0.39
ATM Q13315 1/20 0.37
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21138526 1.00 RECQL (0.54) RECQLMGLLACEHSD11B1ALDH1A1
SCHEMBL19223831 1.00 RECQL (0.54) RECQLMGLLACEHSD11B1ALDH1A1
SCHEMBL16279354 1.00 RECQL (0.54) RECQLMGLLACEHSD11B1ALDH1A1
SCHEMBL3054043 0.90 PHGDH (0.42) RECQLMGLLACEHSD11B1ALDH1A1
SCHEMBL11068486 0.90 PHGDH (0.42) RECQLMGLLACEHSD11B1ALDH1A1
SCHEMBL2399008 0.90 PHGDH (0.42) RECQLMGLLACEHSD11B1ALDH1A1
SCHEMBL8957818 0.81 RECQL (0.50) RECQLMGLLACEHSD11B1ALDH1A1
SCHEMBL27470351 0.79 RECQL (0.58) RECQLMGLLACEHSD11B1ALDH1A1
SCHEMBL6627605 0.77 RECQL (0.56) RECQLMGLLACEHSD11B1ALDH1A1
SCHEMBL4678814 0.77 RECQL (0.56) RECQLMGLLACEHSD11B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107312028-B Halogenated organoaminosilane precursors and methods of depositing thin films comprising the same 弗萨姆材料美国有限责任公司 2023-04-14 CN claimed
EP-3004097-B1 KINASE INHIBITORS CHIESI FARM SPA (IT) 2018-01-17 EP disclosed
CN-105131011-B Carbamate bridged ring Xanthone derivative, its preparation method and medical usage 中国药科大学 2017-08-25 CN disclosed
EP-3004098-B1 KINASE INHIBITORS CHIESI FARM SPA (IT) 2017-08-09 EP disclosed
US-8957212-B2 Photobase generator WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2015-02-17 US disclosed
CN-102232065-B Photobase generator WAKO PURE CHEM IND LTD 2014-11-05 CN disclosed
EP-2368875-B1 PHOTOBASE GENERATOR WAKO PURE CHEM IND LTD (JP) 2014-09-03 EP disclosed
US-20110233048-A1 PHOTOBASE GENERATOR WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2011-09-29 US disclosed
EP-2368875-A1 PHOTOBASE GENERATOR Wako Pure Chemical Industries, Ltd. (JP) 2011-09-28 EP disclosed
CN-1058490-C Tetrazolinone derivatives BAYER AGROCHEM KK (JP) 2000-11-15 CN disclosed
EP-0728750-A1 1-Cycloalkenyltetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1996-08-28 EP disclosed
EP-0711761-A1 Tetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1996-05-15 EP disclosed
EP-0695748-A1 Tetrazolinone herbicides NIHON BAYER AGROCHEM K.K. (JP) 1996-02-07 EP disclosed
CN-1102183-A Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones BAYER AGROCHEM KK (JP) 1995-05-03 CN disclosed
EP-0646577-A1 Process for the preparation of 1,4-disubstituted-5(4H)-tetrazolinones NIHON BAYER AGROCHEM K.K. (JP) 1995-04-05 EP disclosed
US-4488993-A Amidinoureas WILLIAM H. RORER, INC. 1984-12-18 US disclosed
US-4326074-A ANTIDIARRHEA AGENTS WILLIAM H. RORER, INC. (US) 1982-04-20 US disclosed
US-4220658-A Treatment of hypertension with amidinoureas WILLIAM H. RORER, INC. (US) 1980-09-02 US disclosed
US-4115564-A Treatment of diarrhea with amidinoureas WILLIAM H. RORER, INC. (US) 1978-09-19 US disclosed
US-4025652-A ANTIDIARRHEA AGENTS WILLIAM H. RORER, INC. (US) 1977-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110233048-A1 PHOTOBASE GENERATOR CYBA, CRY1, GNB1 RECQL 147/4885MGLL 4402/4885ACE 2746/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.