Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CPB1 | P15086 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8653638 | 0.93 | KMT2A (0.61) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL10523690 | 0.87 | L3MBTL1 (0.67) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL10717563 | 0.87 | L3MBTL1 (0.67) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL19674476 | 0.87 | L3MBTL1 (0.67) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL8649949 | 0.86 | L3MBTL1 (0.62) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL7155441 | 0.85 | KMT2A (0.69) | KMT2AMEN1L3MBTL1ALDH1A1PKM | |
| SCHEMBL16623012 | 0.83 | L3MBTL1 (0.60) | KMT2AMEN1L3MBTL1ALDH1A1GAA | |
| SCHEMBL11879235 | 0.83 | KMT2A (0.67) | KMT2AMEN1L3MBTL1ALDH1A1LGALS8 | |
| SCHEMBL18241590 | 0.83 | KMT2A (0.67) | KMT2AMEN1L3MBTL1ALDH1A1PKM | |
| SCHEMBL11881272 | 0.83 | KMT2A (0.67) | KMT2AMEN1L3MBTL1ALDH1A1LGALS8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472379-A | ANTILEUKEMIA AGENTS | SUAMI T (JP) | 1984-09-18 | — | — | US | disclosed |