Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC3R | P41968 | 13/20 | 0.74 |
| ▸ | MC4R | P32245 | 12/20 | 0.74 |
| ▸ | MC5R | P33032 | 13/20 | 0.73 |
| ▸ | CDK4 | P11802 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11471836 | 0.88 | MC3R (0.68) | MC3RMC4RMC5RCDK4ALDH1A1 | |
| SCHEMBL14264727 | 0.88 | MC4R (0.71) | MC3RMC4RMC5RCDK4ALDH1A1 | |
| SCHEMBL11469475 | 0.84 | ALDH1A1 (0.60) | MC3RMC4RMC5RCDK4ALDH1A1 | |
| SCHEMBL11484912 | 0.82 | SMN1; SMN2 (0.71) | CDK4ALDH1A1 | |
| SCHEMBL11066319 | 0.82 | MC4R (0.60) | MC3RMC4RMC5RCDK4TRPM8 | |
| SCHEMBL13965293 | 0.79 | MC4R (0.59) | MC3RMC4RMC5RCDK4ALDH1A1 | |
| SCHEMBL13965294 | 0.79 | MC4R (0.59) | MC3RMC4RMC5RCDK4ALDH1A1 | |
| SCHEMBL7866153 | 0.79 | MC3R (0.69) | MC3RMC4RMC5RCDK4 | |
| SCHEMBL12464095 | 0.79 | NLN (0.66) | MC3RMC4RMC5RCDK4TRPM8 | |
| SCHEMBL35884 | 0.79 | MEN1 (0.68) | MC3RMC4RALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4425351-A | ANTIANOXIC | SYNTHELABO (FR) | 1984-01-10 | — | — | US | disclosed |