Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 17/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 7/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116837 | 0.89 | MAOB (0.52) | MAOBALDH1A1CYP3A4HPGDMAOA | |
| SCHEMBL7963743 | 0.87 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HPGDTP53TSHR | |
| SCHEMBL7963745 | 0.87 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HPGDTP53TSHR | |
| SCHEMBL7963747 | 0.87 | ALDH1A1 (0.53) | ALDH1A1CYP3A4HPGDTP53TSHR | |
| SCHEMBL11458560 | 0.87 | ALDH1A1 (0.53) | MAOBALDH1A1CYP3A4HPGDPPARD | |
| SCHEMBL4441810 | 0.86 | CA12 (0.53) | MAOBALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL9396963 | 0.83 | ALDH1A1 (0.49) | ALDH1A1CYP3A4HPGDMAPK1TP53 | |
| SCHEMBL10350202 | 0.81 | ALDH1A1 (0.54) | MAOBALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL30516203 | 0.81 | HPGD (0.57) | MAOBALDH1A1CYP3A4HPGDMAPK1 | |
| SCHEMBL3829364 | 0.81 | HPGD (0.57) | MAOBALDH1A1CYP3A4HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448729-A | ANTIALLERGENS, ANTIHISTAMINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-05-15 | — | — | US | disclosed |