Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.37 |
| ▸ | SAT1 | P21673 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL112614 | 0.96 | APEX1 (0.46) | CYP2C19KMT2AMEN1GLACYP1A2 | |
| SCHEMBL109309 | 0.94 | ZDHHC20 (0.46) | CYP2C19CYP1A2APEX1KDM1AALDH1A1 | |
| SCHEMBL111177 | 0.88 | SMN1; SMN2 (0.40) | CYP2C19KMT2AMEN1GLAAPEX1 | |
| SCHEMBL21610956 | 0.88 | APEX1 (0.49) | KMT2AAPEX1ALDH1A1KDM4EZDHHC20 | |
| SCHEMBL22291562 | 0.84 | ZDHHC20 (0.56) | ALDH1A1KDM4EZDHHC20ZDHHC2TSHR | |
| SCHEMBL3701815 | 0.82 | ZDHHC20 (0.52) | APEX1ALDH1A1ZDHHC20ZDHHC2EGFR | |
| SCHEMBL3701812 | 0.82 | ZDHHC20 (0.52) | APEX1ALDH1A1ZDHHC20ZDHHC2EGFR | |
| SCHEMBL22187118 | 0.81 | APEX1 (0.51) | APEX1ALDH1A1KDM4EZDHHC20ZDHHC2 | |
| SCHEMBL7532607 | 0.80 | ZDHHC20 (0.60) | APEX1ZDHHC20ZDHHC2EGFR | |
| SCHEMBL109519 | 0.80 | APEX1 (0.44) | KMT2AAPEX1ALDH1A1KDM4EZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424491-A2 | FILM FORMER IN HAIR DYES | Henkel AG & Co. KGaA (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010124897-A2 | FILM FORMER IN HAIR DYES | HENKEL AG & CO. KGAA (DE) | 2010-11-04 | — | — | WO | disclosed |