Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11068855 | 1.00 | NAAA (0.41) | NAAATLR4MAPK1MAPTLMNA | |
| SCHEMBL11068852 | 1.00 | NAAA (0.41) | NAAATLR4MAPK1MAPTLMNA | |
| SCHEMBL11074195 | 0.96 | NAAA (0.38) | NAAATLR4MAPTHTTUSP2 | |
| SCHEMBL11074190 | 0.96 | NAAA (0.38) | NAAATLR4MAPTHTTUSP2 | |
| SCHEMBL11074193 | 0.96 | NAAA (0.38) | NAAATLR4MAPTHTTUSP2 | |
| SCHEMBL11072749 | 0.95 | NAAA (0.37) | NAAATLR4MAPTHTTUSP2 | |
| SCHEMBL11068618 | 0.95 | NAAA (0.37) | NAAATLR4MAPTHTTUSP2 | |
| SCHEMBL11068616 | 0.95 | NAAA (0.37) | NAAATLR4MAPTHTTUSP2 | |
| SCHEMBL11068621 | 0.95 | NAAA (0.37) | NAAATLR4MAPTHTTUSP2 | |
| SCHEMBL11072746 | 0.95 | NAAA (0.37) | NAAATLR4MAPTHTTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434073-A | Perhydrophenanthrene derivatives, their preparation, and their use in liquid-crystalline dielectrics and electro-optical display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-28 | — | — | US | disclosed |