Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | KHK | P50053 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11066756 | 0.98 | HRH1 (0.48) | HRH1SLC6A2SLC6A3HTR1AKHK | |
| SCHEMBL5473677 | 0.81 | HRH1 (0.58) | HRH1SLC6A2SLC6A3HTR1AKHK | |
| SCHEMBL11067192 | 0.81 | NOS3 (0.45) | HRH1SLC6A2SLC6A3HTR1ANCEH1 | |
| SCHEMBL12192613 | 0.80 | IKBKB (0.54) | PIM1PIM2 | |
| Hydrochloric Acid SCHEMBL5460821 | 0.80 | HRH1 (0.57) | HRH1SLC6A2SLC6A3HTR1AKHK | |
| Hydrochloric Acid SCHEMBL11062354 | 0.79 | SMN1; SMN2 (0.45) | HRH1SLC6A2SLC6A3HTR1ANCEH1 | |
| Hydrochloric Acid SCHEMBL2497632 | 0.79 | IKBKB (0.53) | PIM1PIM2 | |
| SCHEMBL11073267 | 0.79 | SLC6A2 (0.49) | HRH1SLC6A2SLC6A3HTR1AHTR2A | |
| SCHEMBL3115926 | 0.74 | SLC6A2 (0.57) | HRH1SLC6A2SLC6A3HTR1AHTR6 | |
| SCHEMBL1229562 | 0.74 | HRH1 (0.62) | HRH1SLC6A2SLC6A3HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443462-A | Antipsychotic 4-(naphthalenyloxy)piperidine derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1984-04-17 | — | — | US | disclosed |