Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | CNR2 | P34972 | 1/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075597 | 0.91 | CNR1 (0.56) | CNR1CNR2THRBALDH1A1KMT2A | |
| SCHEMBL11076275 | 0.91 | CNR1 (0.56) | CNR1CNR2PIK3CDTHRBMAPT | |
| SCHEMBL11081687 | 0.91 | CNR1 (0.59) | CNR1CNR2PIK3CDTHRBMAPT | |
| SCHEMBL11374217 | 0.88 | CNR1 (0.53) | CNR1CNR2THRBMAPTALDH1A1 | |
| SCHEMBL10972699 | 0.86 | CNR1 (0.67) | CNR1CNR2PIK3CDTHRBMAPT | |
| SCHEMBL10974453 | 0.85 | CNR1 (0.69) | CNR1CNR2PIK3CDTHRBMAPT | |
| SCHEMBL11340568 | 0.84 | CNR1 (0.52) | CNR1CNR2PIK3CDTHRBMAPT | |
| SCHEMBL11071848 | 0.83 | CNR1 (0.57) | CNR1CNR2PIK3CDTHRBMAPT | |
| SCHEMBL11070514 | 0.82 | CNR1 (0.57) | CNR1CNR2PIK3CDTHRBMAPT | |
| SCHEMBL10973972 | 0.82 | CNR1 (0.57) | CNR1CNR2THRBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451467-A | HYPOTENSIVE AGENTS | Ishikawa, Masayuki (JP) | 1984-05-29 | — | — | US | disclosed |
| EP-0056637-A1 | 4(3H)-quinazolinone derivatives, process for production thereof and pharmaceutical compositions comprising said compounds | Ishikawa, Masayuki (JP) | 1982-07-28 | — | — | EP | disclosed |