Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.43 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071848 | 0.92 | CNR1 (0.57) | CNR1CNR2PIK3CDTHRBMAPT | |
| SCHEMBL11340568 | 0.92 | CNR1 (0.52) | CNR1CNR2PIK3CDTHRBMAPT | |
| SCHEMBL10973972 | 0.91 | CNR1 (0.57) | CNR1CNR2THRBALDH1A1KMT2A | |
| SCHEMBL11070514 | 0.91 | CNR1 (0.57) | CNR1CNR2PIK3CDTHRBMAPT | |
| SCHEMBL11068971 | 0.91 | CNR1 (0.58) | CNR1CNR2PIK3CDTHRBMAPT | |
| SCHEMBL11074709 | 0.90 | CNR1 (0.56) | CNR1CNR2THRBALDH1A1ADORA1 | |
| SCHEMBL11079598 | 0.90 | CNR1 (0.56) | CNR1CNR2THRBALDH1A1ADORA1 | |
| SCHEMBL10972776 | 0.89 | CNR1 (0.54) | CNR1CNR2THRBMAPTALDH1A1 | |
| SCHEMBL11374217 | 0.89 | CNR1 (0.53) | CNR1CNR2THRBMAPTALDH1A1 | |
| SCHEMBL11072620 | 0.88 | CNR1 (0.53) | CNR1CNR2MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451467-A | HYPOTENSIVE AGENTS | Ishikawa, Masayuki (JP) | 1984-05-29 | — | — | US | disclosed |
| US-4276295-A | VASODILATORS, HYPOTENSIVE, ANTIATHEROSCLEROTIC | Ishikawa, Masayuki (JP) | 1981-06-30 | — | — | US | disclosed |